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Adults need around 2.4 micrograms (mcg) of vitamin B12 a day, and women who are pregnant or breastfeeding need more

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In contrast to the placebo-treated subjects who experienced minimal changes in body weight over the 16-week treatment period, the pramlintide-treated subjects attained significant weight loss from baseline as early as week 2, which was progressive up to week 16, with no evidence of a plateau