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Plant Physiol 114:275284 Johnston EJ, Rylott EL, Beynon E, Lorenz A, Chechik V, Bruce NC (2015) Monodehydroascorbate reductase mediates TNT toxicity in plants

FIGURE 3 Polymer-based coatings, such as poly (ethylene glycol) (PEG) and poly (lactic-co-glycolic acid) (PLGA), are widely used to enhance the dispersion, biocompatibility, and stability of CeO 2 nanoparticles (NPs)

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There has been a concern that high doses can raise the level of a substance called TMAO (linked in some studies to a greater risk of heart disease), but the evidence is not clear-cut, and the doses used in most studies (about 2,000 mg a day) are considered safe