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I administer B12 injections subcutaneously, which means right under the skin and not into the muscle

Common research dose 300-500 mcg/day in research planning context, drawn from the dose range used across the published Phase 1/2 trials

IGF-1 reduces serum GH levels (via somatostatin negative feedback in the pituitary) which in turn suppresses GH actions in the liver, thus enhancing insulin actions in this organ [165]

Although there are alternative options of B12 supplemantation, such as oral pills, Vitamin B12 injections are the most effective delivery approach as they are best absorbed by th body since they bypass digestion by the stomach and intestines