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tuberculosis H37Rv strain (ATCC 27294) were cultured in 50 ml of Middlebrook 7H9 (Becton Dickinson, Sparks, MD, USA), supplemented with oleic acid, bovine albumin (Fraction V), dextrose, and catalase (OADC, Becton Dickinson) enrichment and 0.05% Tween 80 (Sigma-Aldrich) contained in a 125-ml Erlenmeyer flask with a plain bottom (Nalgene, 4112-0125, NY, USA)

Bismuth quadruple therapy or regimens containing levofloxacin are preferred salvage regimens (Chey 2017)

This is where bioavailability becomes the most important part of the conversation

This is one reason why manufacturers recommend keeping the medication in its original packaging