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2.2.1 Morphological changes Morphologically, microglia have the ability to adopt different morphotypes depending on their state of activation, from quiescent (branched microglia) to hyperbranched, activated, amoeboid or rod microglia (de Hoz et al., 2013

INTRODUCTION Cellular antioxidant networks are essential for maintaining redox homeostasis, balancing the suppression of oxidative damage with the controlled transmission of redox signals that shape cell fate decisions

Specifically, it has been reported that the alteration of DNA methylation status at N6-adenine may have a dual role in cancer, acting either as a tumor promoter or as a suppressor depending on the target gene [39]

We found an absolute decrease in the proportion who discontinued treatment of 7.0% (95% CI 5.0 to 9.0) in June-Dec 2020, and discontinuation remained below expectation in 2021 and 2022