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CD4 + T-cell polarization toward IFN- + Th1/Th17 phenotypes (109) and increased B-cell infiltration (51, 76) synergistically counteracting Treg-mediated immunosuppression (108)

In extreme cases, the patient may even seek amputation as a means to alleviate their suffering (97)

Disruption of brainstem monoaminergic fibre tracts in multiple sclerosis as a putative mechanism for cognitive fatigue: a fixel-based analysis

Weinberg 1 and Therese Bittermann 1 , (1)University of Pennsylvania, (2)University of Pennsylvania, Philadelphia, PA, United States Background: Satellite liver transplant clinics are increasingly common at transplant centers to improve access to liver transplantation