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Curr Med Chem 19(24):41574174 Liu E, Schmidt ME, Margolin R, Sperling R, Koeppe R, Mason NS, Klunk WE, Mathis CA, Salloway S, Fox NC, Hill DL (2015) Amyloid- 11C-PiB-PET imaging results from 2 randomized bapineuzumab phase 3 AD trials

Among them PAH, which suggests that PKD3 plays a role in AAs metabolism

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Without clinical data, an absolute upper limit cant be established