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This association is particularly intriguing because CBS is the most asymmetric of all neurodegenerative parkinsonian disorders [ 95 ]

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Alternatively, due to the broad-spectrum anti-inflammatory possessions of IVIG, this treatment can be combined with IL-1 and IL-6 targeted-immunotherapies, which show promising responses to explore therapeutic effects of additive or synergistic therapy [76, 78, 98]