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Other MDM2 antagonists include AMG-232, HDM201, BI 907828, and ALRN-6924 (Carneiro and El-Deiry, 2020

Difluoromethylornithine combined with a polyamine transport inhibitor is effective against gemcitabine resistant pancreatic cancer

Orlistat is classified as a lipase inhibitor

Given the susceptibility of Cys111 to oxidative modifications in SOD1-ALS and previous work on cisplatin and BMOE, we undertook a crystallographic screening of a small library of cysteine-reactive compounds known to have favourable properties (Supplementary Fig