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We began to observe the accumulation of ferroptotic cells, as detected upon the intercalation of a cell-impermeable fluorescent dye within nuclear DNA, following 24 h of cystine deprivation (Supplementary Fig

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Its multifaceted nephroprotective mechanism emerges through dual pathways: initially, the inherently minimal endogenous acid load characteristic of plant-predominant nutrition effectively counterbalances metabolic acidosis that typically accelerates renal functional deterioration in CKD (Chauveau et al., 2019