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When tested at 10 M, -Glu-Glu was the only one among the - L-Glu-AAs tested to elicit significant excitatory action evidenced by a Ca 2+ increase (68.5 11.10% after normalizing the response elicited by the dipeptides to the response induced by 10 M glutamate

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Vaccine development for diseases like dengue faces significant challenges, including the issue of Antibody-Dependent Enhancement (ADE), where antibodies from a previous infection may worsen a subsequent infection with a different virus type [117]