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Over 75% of users in a Southeast Asian study reported noticeable skin lightening within 1012 weeks, with minimal complications when administered by licensed professionals

Larsen RH, Utke Rank C, Grell K, et al

This phenomenon may therefore play an important role in cryoprotection or radioprotection induced by DMSO 37,38 and can also modify the response of yeast to substances dissolved in DMSO

In brain, KYN is metabolized by microglia to the neurotoxic metabolite QUIN and by astrocytes to the beneficial metabolite kynurenic acid (KynA), thus, QUIN is increased and KynA is decreased in MDD patients brain