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In recent years, the incidence of BLI has increased, largely attributed to advancements in diagnostic technologies such as CT imaging

The potential role of maternal exposures during pregnancy, namely tobacco, alcohol, drugs and medication, chronic or infectious diseases, and vitamin supplements, has not yet been unequivocally established

Tumor necrosis factor-alpha (TNF-)and Interleukin-1 (IL-1) as well as other cytokines involved in homeostasis or neuroinflammation and illness, are produced by microglia [34]