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At the same time, the expression levels of pro-caspase-3 and IB-a were significantly upregulated upon pretreatment of human colon cells with NF-B activity-inhibiting drugs, suggesting that inhibition of NF-B can reduce the apoptosis of intestinal epithelial cells (Cao et al., 2020)

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Some ternary copper complexes can interact with mitochondria in tumor cells or normal cells, blocking the process of oxidative phosphorylation, inhibiting respiration, and showing antitumor activity against various tumor cells both in vivo and in vitro (116)

Ferric carboxymaltose in heart failure with iron deficiency