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Description

131 In a few instances, leukocyte dysfunction associated with Class I variant G6PD deficiency has been described

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Its molecular core involves the receptor interacting serine/threonine kinase 1 (RIPK1)-receptor interacting serine/threonine kinase 3 (RIPK3)-mixed lineage kinase domain like pseudokinase (MLKL) signaling axis (119)