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Personalized interventions, such as tailored strength training programs or surgical options, can be developed to address these anatomical risk factors

mitochondrial metabolism and bioenergetics (AMPK1, PI3K, SIRT1)

Chelation therapy Chelation therapy is a medical procedure that involves the administration of chelating agents to remove heavy metals from the body

Another study confirmed this finding, showing that during hindlimb unloading and reloading, lipid peroxidation in skeletal muscles significantly increases, accompanied by dysregulation of heat shock proteins (HSPs), especially a decrease in Hsp70 and Hsp25 expression, which further aggravates muscle damage and atrophy (67)