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As expected, the increased G6pc expression in Insr P1195L/ +/HFD liver on re-feeding was markedly reduced by the transplantation of wild-type subcutaneous fat to the mice (Fig

During the early stages of PD, [11C]BU99008 PET showed an increased uptake in frontal, temporal, parietal, occipital and insula cortices and subcortical regions such as caudate, putamen, thalamus and brainstem as compared with healthy controls, whereas in advanced stages these differences disappeared 365

Effect sizes and corresponding 95% confidence intervals are also shown within the Figure Legends

It's executing the reconstitution without compromising the peptide structure