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TISMO: syngeneic mouse tumor database to model tumor immunity and immunotherapy response

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Structural Changes in the Heart Long-term overweight and hypertension can cause: Left ventricular hypertrophy (thickening of heart muscle) Reduced cardiac efficiency Increased risk of heart failure The heart must work harder to pump blood against higher pressure

metastatic tumors rely on pyruvate, glutamine, and lipid metabolism, and cancer stem cells depend on mitochondrial metabolisms such as OXPHOS and aerobic glycolysis [12,37]