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Daratumumab is used for treating multiple myeloma (MM), a malignancy arising from CD38 high plasma cells (79), which could be a contributing factor to the uncontrollable increase in EBV viremia and small burst of virion production as evidenced by the detection of encapsidated viral DNA

Given that several client proteins display acidic residues at the C-terminal position, our data are suggestive of a broad modulatory function of this residue in secretory trafficking

The twice-daily structure requires strict adherence to 12-hour intervals

We have shown the difference between VRK2-WT cells and VRK2-KO cells in the sensitivity to GSH inhibition and noted that sensitive cells exhibited surged ROS levels following GSH inhibition (Fig