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Front Cell Neurosci 7:39

Havel received his BA form Reed College in Portland, Oregon in 1946, completed his internship a Medicine at New York Hospital (Cornell University Medical School in 1949, and received an MS and MD degrees from the University of Oregon Medical School in 1949

TSHR-CAR-T was constructed by incorporating the first extracellular domain (21-413aa) of TSHR, fused with the CD8 transmembrane and intracellular signaling domain (4-1BB), which can recognize and effectively eliminate TRAb-producing B lymphocytes both in vitro and in vivo ( 4.7 Type 1 diabetes First-generation CD3--CAR T cells, expressing the 2-microglobulin component of MHC I and targeting the anti-InsB15-23-H-2Kd TCR, significantly reduced insulitis and protected non-obese diabetic (NOD) mice from T1DM ( in vitro , due to the broad expression of the Hpi2 antigen across multiple cell types

Dercksen, M