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Mechanism of action Direct arteriole dilation occurs

PLoS One 7 , e40407, doi:10.1371/journal.pone.0040407 (2012)

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Am J Physiol Endocrinol Metab 301:E1220E1228 Kayal RA, Tsatsas D, Bauer MA, Allen B, Al-Sebaei MO, Kakar S, Leone CW, Morgan EF, Gerstenfeld LC, Einhorn TA, Graves DT (2007) Diminished bone formation during diabetic fracture healing is related to the premature resorption of cartilage associated with increased osteoclast activity