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Notably, despite the dramatic difference in d 3 -TMAO production from oral d 3 -l-carnitine in omnivores versus vegans/vegetarians, the difference observed in the first step of that gut microbiotamediated transformation, conversion of d 3 -l-carnitine to d 3 -BB, was not significant, and if anything showed a trend toward a lower conversion rate in the omnivores ( P = 0.051

Additionally, CS exposure also disrupts the extracellular matrix during COPD (Shapiro and Ingenito, 2005), which could subsequently promote FAO in EpiC (Schafer et al., 2009)

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