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doi: 10.3389/fncel.2022.980722 124 WangZ.XieX.XueY.ChenY

Epithalon Peptide Characteristics Molecular Formula: CHNO CAS Number: 307297398 Synonyms: Epitalon, Epithalon, Epithalone, AEDG Molar Mass: 390.35 g/mol ( 390.34 Da) Appearance: White to off-white lyophilized powder Solubility: 50 mg/mL in water (128 mM) Soluble in DMSO up to ~250 mg/mL (496 mM) Storage Recommendations Dry, lyophilized form: Store at 20 C (preferably 80 C for long-term) In water/PBS/Saline store at 80 C up to 6 months, or 20 C up to 1 month Epithalon vs FOXO4-DRI vs Thymalin Comparison Safety and Side Effects in Studies In one 6.5-month study on C3H/He mice receiving 0.1 g Epitalon daily, no toxic effects were observed, even as tumor incidence and metastases decreased [6]

In this non-placebo-controlled trial, eGFR statistically increased after 4 and 8 weeks compared with baseline (2.8 mL/min/1.73 m 2 and 7.2 mL/min/1.73 m 2 at each time point, respectively) [55]

The first of these, GCLC-a (Figure 2B), would cleave after position 217, and is an exact match to P4-P1 of nsp5/6, but with an A in P1, a highly favorable residue for that position, although SCoV has a G there, and SCoV2 has an S