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Research Benefits Dihexa and Dementia Preclinical studies suggest that Dihexa may influence neurotrophic factors involved in synaptic formation, which could be relevant to neurodegenerative research

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Notably, in the setting of high-frequency and prolonged sympathetic activation such as during acute myocardial ischemia, additional sympathetic co-transmitters other than norepinephrine (NE) are co-released from sympathetic post-ganglionic efferent fibers, including ATP, galanin and neuropeptide Y (NPY) (Herring 2015)

In rodent studies, degeneration may also be applicable to chronic debility, but more often it is used to reflect acute or chronic cytological alterations with characteristic morphological features