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Administration of CB-1158 (a small molecule inhibitor of arginase) can slow tumor growth rates, block myeloid cell-mediated suppression of T-cell proliferation, and increase the number of tumor-infiltrating CD8 + T cells and NK cells in mouse models of multiple tumors

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doi: 10.1016/j.cmet.2013.12.008 145

Similar content being viewed by others Introduction Acute kidney injury (AKI) is a common complication that occurs in approximately 20% of hospitalized patients 1 and is associated with increased mortality, regardless of whether renal replacement therapy (RRT) is required