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The Air Force will not even evaluate a D2P2 if this file set fails to establish scientific and technical merit, or if the work was done under any prior SBIR/STTR

Oral administration is not effective because the peptide fragments are broken down in the digestive tract before they can reach systemic circulation

In clinical studies targeting obesity, particularly in the phase 3 trials based on the SURPASS program, tirzepatide demonstrated outstanding weight reduction benefits, with some patients achieving a weight loss of up to 22.5%

Although there are several known risk factors for depression that were not included in this analysis, to function as a confounder, these factors would also need to be associated with elevated body temperature