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10.1016/j.jep.2021.114778 26 BurkhardP.EberlD

Furthermore, PIT using the T-cell epitope of AK encapsulated with the TLR9 agonist CpG-ODN in nanoparticles, demonstrated significant attenuation of Th2-mediated allergic responses, reducing anaphylactic symptoms and Th2 cytokines while enhancing Th1 cytokine expression in a shrimp allergy model [162]