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In several preclinical studies, melatonin has proven itself worthy in the protection of neurons against iron-induced toxicity [396,397,398,399]

AUA categorizes body of evidence strength as Grade A (well-conducted RCTs or exceptionally strong observational studies), Grade B (RCTs with some weaknesses of procedure or generalizability or generally strong observational studies), or Grade C (observational studies that are inconsistent, have small sample sizes, or have other problems that potentially confound interpretation of data)

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After 72 h, supernatants were harvested and the concentrations of IL4 (CAT#CSBE04634m