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They are not approved for human use outside of registered clinical trials and are not FDA-approved as therapeutic agents

Consider these facts: The net clearance of L-lactate from the blood into the liver 1.85-3.3-fold faster than the net clearance of D-lactate

Inhibition of histone deacetylase activity down-regulates urokinase plasminogen activator and matrix metalloproteinase-9 expression in gastric cancer

This perspective is strengthened by recent findings demonstrating that lipid-rich structures, most notably the myelin sheaths that envelop axons, can act as significant oxygen reservoirs