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When threats to homeostasis occur such as infection, hypoxia, and starvation (364, 365), they involve immune and inflammatory processes that influence energetics and metabolism (366, 367)

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Benefit of Policies As indicated in the CY 2026 OPPS/ASC proposed rule (90 FR 33856), although we cannot quantify the benefits of including additional data elements and encoding such data in the CMS required MRF template, we believe any opportunity to provide further context about standard charges, including through the addition of contextual information when the payer-specific negotiated charge is based on a percentage or algorithm, will be helpful to all consumers of the MRF as they analyze the data to identify cost savings and ways to stimulate market competition