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Monini S, Lazzarino AI, Iacolucci C, et al

Moreover, the risk of vitamin B12 deficiency also increases with increased metformin dose and duration of its use

We are maybe in an unusual position whereby while we may not have the direct clinical trial data to definitively say they do or do not work, we have been undertaking full (minimum 70 marker) detailed venous screening (and body composition analysis) with people using since June (around 150 people) so we have that internal evidence