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Inhalation drug delivery systems provide a potential strategy for targeted LC therapy by allowing direct deposition of drugs into the lungs, therefore improving therapeutic effectiveness and reducing systemic side effects

In this manuscript, we propose that an integrative neurogenomics workflowcombining multi-omic phenotypeoriented whole-exome sequencing, biologically-oriented common variant burden profiling, biochemical markers, functional metagenomic data, and multidisciplinary clinical interpretationcan generate testable, personalized diagnostic and therapeutic hypotheses in neurodegenerative disorders

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