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10.3390/cells11152262 131 GongL.HuangD.ShiY.LiangZ.BuH

Indeed, overexpression of wild-type IRP2 significantly increased tumor burden in a mouse xenograft model, but when a mutant version IRP2 lacking the 73 amino acid insert was overexpressed in the same model, this response was blunted ( IRP2 has also been implicated in tumor progression via its capacity to suppress translation of the tumor suppressor gene, tumor protein p53 (TP53) (Zhang et al., 2017)

Nonsteroidal Anti-Inflammatory Drugs in Animals

Interactions between hormone and redox signalling pathways in the control of growth and cross tolerance to stress