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111 A commercially available ITM product, Multimin 90 from Axiota Animal Health that contains Zn (60 mg/ml), Cu (15 mg/ml), Mn (10 mg/ml), and Se (5 mg/ml) has demonstrated rapid absorption, leading to an increase in blood TM concentrations within 8 hours after injection, maintaining elevated circulating concentrations for 24 hours, after which they are stored in liver

The doses of ZnO NPs used were according to previous work 32

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Shen Chuen Khaw 1, Zhen Zhe Wong 2, Richard Anderson 3, Sarah Martins da Silv l-carnitine and l-acetylcarnitine supplementation for idiopathic male infertility National Library of Medicine, 2020 Dec 23;1(1):67-81