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For example, knockout of virulence-related genes in some native live bacteria reduces their potential pathogenicity while retaining their beneficial functions [111]

napus and analyzed their evolution and syntenic relationships

doi:10.1111/j.1574-6976.2001.tb00570.x

This process is morphologically marked by small mitochondria with condensed membrane densities, and biochemically by iron overload and GSH depletion, leading to loss of antioxidant defense and irreversible oxidative damage ( 3.2 Key molecular drivers of ferroptosis Iron Overload: Excess intracellular ferrous iron (Fe 2+ ) catalyzes the Fenton reaction, producing hydroxyl radicals (OH) that initiate lipid peroxidation cascades