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The expression of CD44 on CD4 + T-cells is known to promote the occurrence of type 1 helper (Th1) responses and the generation of inflammatory cytokines ( + DCs, which were characterized by the expression of co-stimulative markers CD80 and CD86 ( + Treg cells is crucial for maintaining intestinal immune tolerance ( Figure 2E )

In addition, no significant loss in body weight was observed in each liposome group compared with the CPT11 and TPT groups, in which body weights decreased to a different extent during treatment (Fig