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Menadione induces changes in the membrane electrical properties associated with downregulation of insulin receptors in human erythrocytes

doi: 10.3390/ijms23073610 158 McKinney-AguirreC

www.ema.europa.eu

Increasing evidence indicates that dysregulation of mitochondrial quality control, including impaired mitophagy (PINK1/Parkin axis), altered fission-fusion balance (DRP1, MFN2, OPA1), and destabilized mitochondrial-ER contact sites, contributes to sustained ROS leakage and defective bioenergetics (Cheng et al., 2024