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Graphical abstract Similar content being viewed by others Introduction Age-related macular degeneration (AMD) is a leading cause of vision loss globally, affecting ~ 150 million people in 2020, with that number expected to increase by nearly 50% by 2040 [1, 2]

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Glutamate is the primary excitatory neurotransmitter in the mammalian brain, and it participates in diverse physiological processes such as learning, memory, and neuronal development (Yu et al., 1984