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In relapsed or refractory myeloma (R/R MM) patients, the CD38 expression levels are relatively high in NK cells, regulatory B cells (Bregs), Tregs and myeloid-derived suppressor cells (MDSCs) compared with CD8 + and CD4 + T cells, indicating that CD38 is involved in providing the immunosuppressive environment for tumor growth [19]

Furthermore, LL-37 can neutralize endotoxins, reducing inflammation caused by microbial products (Davidson et al., 2004)

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The product is manufactured at FDA-registered facilities under Current Good Manufacturing Practice (cGMP) regulations