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This constraining to equality did not lead to a significant reduction in model fit (CFI = 0.002, RMSEA = 0.002, SRMR = 0.002), thus supporting metric invariance implying equal salience of factors for both male and female students (Table 4) (228)

Moreover, the metabolic reprogramming in response to oncogenic mutations plays a critical role in tumorigenesis deeply altering intracellular and extracellular metabolites, and affecting gene expression, differentiation and tumour microenvironment [3]