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However, the anti-inflammatory effects of estrogen on mRNA stability have not been investigated in the same way and may provide insight into regulation of growth factors and cytokines involved with estrogenic modulation of angiogenesis (Fieber et al., 2006

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And that's their stance

Some animal research suggests it has potent antiepileptic and neuroprotective effects and, when used correctly, should be safe for healthy adults.25 However, because supplements including nootropic ones arent regulated by the FDA, theres a possibility that supplements containing Huperzia serrata can be dangerous