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The nuclear receptor transcription factor Nurr1 orchestrates DA neuron maturation, functional regulation, and lifelong maintenance, with its expressioninitiating in the VM at embryonic day 10.5 (in mice) and persisting throughout adulthoodmediating perinatal stress response adaptation (Zetterstrm et al., 1996)

At 1mg per vial, each unit provides approximately 100 research doses at a standard 10mcg dose

It is characterized by high hospital costs, morbidity, and mortality, and it provokes a high hospitalization rate and inpatient mortality [376,377,378]