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Description

Rivero-Pino F, Espejo-Carpio FJ, Guadix EM

Aging Cell 10 , 392402 (2011)

This surge is driven by population aging, increased life expectancy, regional demographic transitions and projections suggest the global PD population may exceed 25 million by 2050 [2]

However, clinical translation is hindered by regulatory/scalability challenges, cost barriers, preclinicalclinical translation gaps, and technical limitations (e.g., wireless control precision and in vivo stability)