hypothesis glutathione persister cells

hypothesis glutathione persister cells cancer cells: Iron addiction and vulnerability to ferroptosis: Molecular Cell Drug-tolerant persister cancer cells are

Name: hypothesis glutathione persister cells cancer cells: Iron addiction and vulnerability to ferroptosis: Molecular Cell Drug-tolerant persister cancer cells are
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Drug tolerant persister cancer cells are vulnerable to GPX4 inhibition Nature Mechanism of Drug Tolerant Persister Cancer Cells: The Landscape and Clinical Implication for Therapy Journal of Thoracic Oncology Drug tolerant persister cancer cells are vulnerable to GPX4 inhibition PMC Frontiers Exogenous cystine increases susceptibility of drug resistant Salmonella to gentamicin by promoting oxidation of glutathione metabolism and imbalance of intracellular redox levels

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, more than one thousand fold higher) concentration of glutathione alone, not including that of the thiol groups of other non-protein and protein components

10.1111/apm.12018 159

In addition to A 1-42 , similar amyloid aggregates have been found in many diseases, such as islet amyloid polypeptide in type II diabetes 187 , human calcitonin in thyroid cancer 188 , -synuclein in Parkinsons disease 189 , and mutated SOD1 in amyotrophic lateral sclerosis 190