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This effect varies in different reagents

Extensive non-selective growth on YES plates (patching every 2 days for 14 days) produced cup1-epi20yp which had partially lost resistance to caffeine

doi: 10.3389/fphar.2025.1563676 Received 20 January 2025 Accepted 08 April 2025 Published 29 April 2025 Volume 16 - 2025 Edited by Hua Yang, China Pharmaceutical University, China Reviewed by Dechao Feng, University College London, United Kingdom Yin Wan, Nanchang University, China Updates Copyright 2025 Li, Liu, Song, Zhou, Tang, Xu, Shi, Liu and Ni