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Through integrating findings from recent studies, this work aims to shed light on the potential of microbiota-targeted therapies in managing diseases that involve the gut, liver, and kidneys (Guo et al., 2 Composition and function of gut microbiota The gut microbiota, a diverse community of microorganisms living in the gastrointestinal tract, is vital for human health

doi: 10.1016/j.chemosphere.2012.10.066 28 GuptaD

Additionally, qRT-PCR analysis revealed that K-Hcy-modified HMGB1/2 significantly suppressed SLIT2 mRNA expression in endothelial cells (Figure S6E)

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