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Additionally, polyphenols strengthen the body's natural antioxidant defenses by directly inhibiting pro-inflammatory and the nuclear factor erythroid 2-related factor 2 (Nrf2) pathways, a crucial regulator of antioxidant defense mechanisms, which are activated by these compounds

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Kunnumakkara, et al., Cancer Res., 67(8):3853-61 (2007)

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[18] Hantoushzadeh S, Shamshirsaz AA, Aleyasin A, Seferovic MD, Aski SK, Arian SE, et al

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