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Rantes and monocyte chemoattractant protein-1 (Mcp-1) play an important role in the inflammatory phase of crescentic nephritis, but only mcp-1 is involved in crescent formation and interstitial fibrosis

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They found that vitamin D supplementation resulted in a statistically significant reduction in risk of RTIs among all participants, with a 12% lower risk of acute RTIs for those supplementing with vitamin D versus those with no supplementation