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Intermittent and low-level inhibition of key UPS components, which triggered only very mild stress in the differentiating hMSCs, had surprisingly distinct effects on the bone-like material they formed, altering its stiffness and the amount of protein and crystalline mineral it contains, and affecting its micro- and ultra-structural organization (53)

Results summaries and comparisons between treatments are shown in Supplementary file 6

Comparative Biochemistry and Physiology Part c: Toxicology & Pharmacology, 221 , 2128

The importance of AKT in cancer-related IGF signaling is further exemplified by its role in invasion and metastasis [33]