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10.1002/ptr.6730 [DOI] [PMC free article] [PubMed] [Google Scholar] Santalla A., Nogales-Gadea G., rtenblad N., Brull A., de Luna N., Pins T., et al

Standen BT, Peggs DL, Rawling MD, Foey A, Davies SJ, Santos GA, Merrifield DL (2016) Dietary administration of a commercial mixed-species probiotic improves growth performance and modulates the intestinal immunity of tilapia, Oreochromis niloticus

2.2.3 DHODH pathway Dihydroorotate dehydrogenase (DHODH) is a mitochondrial inner membrane enzyme that plays a role in important metabolic pathways such as cytochrome P450, purine synthesis, and fatty acid metabolism (75, 76)

MDA can affect the activity of respiratory chain complexes and critical enzymes in mitochondria and aggravate membrane damage